Diagnostic value of magnetic resonance diffusion tensor imaging in acute occult cervical spinal cord injury
Zhou Bin1，Zhang Huinan1，Gao Wen1，Zeng Xianjun2
1Department of Magnatic Resonance Imaging, Jiujiang Hospital of Traditional Chinese Medicine, Jiujiang 332000， China； 2Department of Radiology, the First Affiliated Hospital of Nanchang University, Nanchang 330000, China
Abstract：ObjectiveTo investigate the value of magnetic resonance diffusion tensor imaging (DTI) in the diagnosis of acute occult cervical spinal cord injury(CSCI). MethodsSubjects were selected from the patients who were treated in orthopedics and neurosurgery department in hospital from June 2016 to July 2017. All the subjects had a clear history of trauma within 72 hours, and a non apparent abnormality of T2WI sequence and STIR sequence examination. Thirty patients joined the injured group and the control group contained 30 healthy volunteers. Both of them accepted MR sequence and DTI sequence examination respectively. Data processing and analysis were performed on both groups of DTIs to obtain diffusion tensor tractography (DTT). The fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values of the two groups were measured respectively. Independent samples ttest was used to compare the differences between the two groups. ResultsThe FA value of injured group (0.53±0.22) was significantly lower than that of control group (0.65 ± 0.12), the difference was statistically significant (t=5.00,P<0.01). The ADC value ［(1.15±0.28)×10-3mm2/s］ in injury group was significantly higher than that in the control group ［(1.04±0.57)×10-3mm2/s］, the difference was statistically significant (t=11.20,P<0.01). The DTT of the cervical spinal cord of injury group showed sparse, twisted and broken white matter in the damaged area.ConclusionsThe FA and ADC value of DTI can quantitatively analyze the severity of spinal cord white matter injury in CSCI patients. DTT can accurately depict the location and extent of white matter damage in the spinal cord. It is an important mean for noninvasive diagnosis of occult cervical spinal cord injury and prognosis evaluation.
