The characters of electroencephalogram power in patients with Alzheimer disease
Yangpeng1,4,Yueyang2,Zhou Xiaobao3,Wangyan4
1Deparment of Electroencephalogram,2Department of Psychiatry,3Department of Occupational Medicine,Jining Mental Health Hospital,Jining 272051,China;4Depatment of Neurology,The Affiliated Hospital of Qingdao University,Qingdao 266071,China
Abstract:ObjectiveTo study the change of electroencephalogram (EEG)power in patients with Alzheimer's disease(AD).MethodsThirty patients with AD and thirty healthy people were included.EEG was recorded during eyes-closed resting condition and was transformed to provide estimate for total power,absolute and relative power in delta,theta,alpha and beta activity frequency bands and δ+θ/α+β power radio.ResultsThe power radio of δ+θ/α+β at Fp1,Fp2,F3,F4,C3,C4,P3,P4,O1,O2,F7,F8,T3,T4,T5,T6 in group AD[(1.18±0.27),(1.11±0.30),(1.05±0.36),(1.03±0.31),(1.00±0.33),(1.06±0.36),(0.99±0.38),(1.04±0.37),(0.97±0.37),(1.05±0.38),(0.99±0.33),(1.10±0.23),(0.91±0.28),(0.93±0.32),(1.00±0.40),(0.95±0.34)] were significantly higher than those in controls [(0.65±0.19),(0.63±0.09),(0.59±0.13),(0.55±0.11),(0.54±0.18),(0.49±0.12),(0.50±0.19),(0.47±0.13),(0.40±0.21),(0.40±0.14),(0.61±0.18),(0.59±0.14),(0.59±0.19),(0.54±0.16),(0.45±0.18),(0.50±0.18)] (P<0.05).The power of relative band theta at Fp1、Fp2、F3、F4、C3、C4、P3、P4、O1、O2、F7、F8、T3、T4、T5、T6 in group AD were significantly higher than those in controls (P<0.05).The power of relative band delta at Fp2,F4,C4,P3,P4,O1,O2,F7,F8,T5 in group AD were significantly higher than those in controls (P<0.05,P<0.01).The power of relative band alpha at Fp1,Fp2,F3,F4,C3,C4,P4,O1,O2,F7,F8,T3,T5,T6 in group AD were significantly lower than those in controls (P<0.05). The power of band theta at Fp1,Fp2,F8,T4,P4 in group AD were significantly higher than those in controls (P<0.05).The power of band alpha at Fp1,F3,O1,O2,F7 in group AD were significantly lower than those in controls (P<0.05).The power of band beta at P3,O1,O2,T5 in group AD were significantly lower than those in healthy people(P<0.05).ConclusionsThe quantiative electroencephalography (QEEG )of patients with Alzheimer disease is significantly different from controls,QEEG is helpful to diagnose AD.
杨鹏 岳阳 周效宝 王雁. 阿尔茨海默病患者脑电功率值特征分析[J]. 中华诊断学电子杂志, 2015, 3(1): 36-40.
Yangpeng,Yueyang,Zhou Xiaobao,Wangyan. The characters of electroencephalogram power in patients with Alzheimer disease. zhzdx, 2015, 3(1): 36-40.