The clinical pathological features of rhabdomyosarcoma of the epididymis and literature review
Liao Qianhe1, An Huimin2, Chen Zhiyong3
1Department of Pathology, 3Department of Urology, Shuyang People′s Hospital of Jiangsu, Shuyang 223600, China; 2Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China
Abstract：ObjectiveTo explore the clinical and pathological features of rhabdomyosarcoma of the epididymis. MethodsThree cases of epididymal rhabdomyosarcoma admitted to Shuyang People′s Hospital of Jiangsu from January 2011 to December 2019 were selected. The clinical and pathological features of the 3 cases were studied by pathological examination and immunhistochemical staining. ResultsThe 3 patients with rhabdomyosarcoma of the epididymis were aged 10 years, 23 years and 25 years, respectively. The course of disease was 1 month, 2 months and 4 months, respectively. Among them, 1 case of left epididymis and 2 cases of right epididymis, and all were single nidus. The main clinical symptom was a scrotal mass with progressive enlargement. Both ultrasonography and MRI examination showed epididymal space occupying lesions. Postoperative pathology diagnosed epididymal rhabdomyosarcoma, including 2 cases of alveolar rhabdomyosarcoma and 1 case of embryonal rhabdomyosarcoma. Microscopically, the tumor consisted of primitive mesenchymal cells and differentiated rhabdomyocytes. Immunohistochemically, the tumor cells were positive for myogenin, myogenic differentiation (MyoD1), vimentin and desmin, but negative for neuron specific enolase (NSE), S-100, actin, smooth muscle actin (SMA), CD34, CD99 and cytokeratin-pan (CKpan). ConclusionRhabdomyosarcoma of epididymis is a rare malignant tumour, and early diagnosis and standard treatment can achieve a good prognosis.
廖谦和 安慧敏 陈志永3. 附睾横纹肌肉瘤的临床病理学特征并文献复习[J]. 中华诊断学电子杂志, 2020, 8(4): 270-274.
Liao Qianhe1, An Huimin2, Chen Zhiyong3. The clinical pathological features of rhabdomyosarcoma of the epididymis and literature review. zhzdx, 2020, 8(4): 270-274.
