1Department of Cardiology, 2Department of Medical Ultrasound, Shandong Provincial Qianfoshan Hospital, Shandong University, The First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital), Jinan 250014, China
Abstract：ObjectiveTo investigate the clinical diagnostic features of viral myocarditis to dilated cardiomyopathy. MethodsThe clinical data of a patient who had a 9year transformation from viral myocarditis to dilated cardiomyopathy were retrospectively evaluated. ResultsThe patient utilized drugs with insufficient treatment and suffered chest tightness and palpitations 5 times after a cold in 9 years. The patient's left ventricular ejection fraction and interventricular septal thickness varied significantly over the course of 9 years, and they have been declining since 2018. In June 2017, a cardiac MRI revealed significant ventricular wall weakening, with a maximal left ventricular enddiastolic diameter of 60.15mm. The patient′s genetic test results indicated dilated cardiomyopathy, and the DSP gene′s c.2974.2 A＞G site mutation was discovered. The physiology of the heart remained irreversible even after 9 years of the patient taking medication consistently and attempting to avoid diseaserelevant triggers. ConclusionsPatients who carry relevant pathogenic genes are more likely to develop the dilated cardiomyopathy. For the early identification of the cause and the management of illness development, it is crucial to support individualized precision treatment and the early discovery of the associated pathogenic genes.
收稿日期: 2022-04-18
基金资助:山东省自然科学基金（ZR2019PH057）
通讯作者:
徐瑞， Email:xuruicn@hotmail.com
引用本文:
于晓倩1徐瑞 1黄文2吴霞1赵学强1郑飞1李欣然1. 病毒性心肌炎向扩张型心肌病转变进展的诊断学特征[J]. 中华诊断学电子杂志, 2022, 10(4): 238-242.
Yu Xiaoqian1, Xu Rui1, Huang Wen2, Wu Xia1, Zhao Xueqiang1, Zheng Fei1, Li Xinran1. Clinical diagnostic features of viral myocarditis to dilated cardiomyopathy. zhzdx, 2022, 10(4): 238-242.
