Abstract：Apelin is a multifunctional bioactive peptide that exerts corresponding biological effects by binding to its receptor APJ. The apelin/APJ system, as an important regulator of the body, is widely involved in physiological and pathological processes of the cardiovascular system, metabolic system, nervous system, and other aspects. An increasing number of studies indicate that the apelin/APJ system can serve as a key target for prevention and control, and prognosis of clinical diseases. This article provides a review of the physiological and pathological effects of the apelin/APJ system and explores the specific mechanisms and the prospects for its clinical applications, in order to promote the development of new drugs and look for new treatment strategies.
王睿浩 姜云璐 田艳君. Apelin/APJ系统生理病理作用的研究进展[J]. 中华诊断学电子杂志, 2024, 12(2): 138-143.
Wang Ruihao1, Jiang Yunlu1, Tian Yanjun2. Research progress on the physiological and pathological effects of apelin/APJ system. zhzdx, 2024, 12(2): 138-143.
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